Polyamines

Polyamines:

• For regulating your immune system.
• A key chemical produced by methylation.

Snyder-Robinson syndrome:

• Spermine synthase enzyme is involved in the production of spermine, which is a type of small molecule called a polyamine.

Polyamines Interact with Diseases:

• Colorectal cancer 23.67
• Inflammatory bowel disease 9.82
• Breast carcinoma 7.85
• Colonic neoplasm 7.04
• Ovarian Cysts 5.39
• Uterine fibroid 5.37
• Arthritis, Experimental 4.84
• Amyotrophic lateral sclerosis 1 4.83
• Diabetes Mellitus, Type 2 4.54
• Renal cell carcinoma 4.51
• Glomerulonephritis 4.4
• Papilloma 4.28
• Liver Cirrhosis 4.09
• Status Epilepticus 4.09
• HIV Infections 4.03
• Skin Neoplasms 3.94
• Cocaine dependence 3.83
• Colorectal cancer 23.67
• Inflammatory bowel disease 9.82
• Breast carcinoma 7.85
• Colonic neoplasm 7.04
• Ovarian Cysts 5.39
• Uterine fibroid 5.37
• Arthritis, Experimental 4.84
• Amyotrophic lateral sclerosis 1 4.83
• Diabetes Mellitus, Type 2 4.54
• Renal cell carcinoma 4.51
• Glomerulonephritis 4.4
• Papilloma 4.28
• Liver Cirrhosis 4.09
• Status Epilepticus 4.09
• HIV Infections 4.03
• Skin Neoplasms 3.94
• Cocaine dependence 3.83

Genes:

• ODC1
• JUND
• SFRP1
• SFRP2
• SFRP4
• GATA5
• SFRP5
• SMS gene-involved in the production of spermine, which is a type of small molecule called a polyamine.
• SAT1 gene-an enzyme in the catabolic pathway of polyamine metabolism.
• TGM6 gene-cross-linking of proteins and the conjugation of polyamines to proteins.
• MTAP gene-This gene encodes an enzyme that plays a major role in polyamine metabolism.