Polyamines

Polyamines:

    • For regulating your immune system.
    • A key chemical produced by methylation.

Snyder-Robinson syndrome:

  • Spermine synthase enzyme is involved in the production of spermine, which is a type of small molecule called a polyamine.

Polyamines Interact with Diseases:

    • Colorectal cancer 23.67
    • Inflammatory bowel disease 9.82
    • Breast carcinoma 7.85
    • Colonic neoplasm 7.04
    • Ovarian Cysts 5.39
    • Uterine fibroid 5.37
    • Arthritis, Experimental 4.84
    • Amyotrophic lateral sclerosis 1 4.83
    • Diabetes Mellitus, Type 2 4.54
    • Renal cell carcinoma 4.51
    • Glomerulonephritis 4.4
    • Papilloma 4.28
    • Liver Cirrhosis 4.09
    • Status Epilepticus 4.09
    • HIV Infections 4.03
    • Skin Neoplasms 3.94
    • Cocaine dependence 3.83
    • Colorectal cancer 23.67
    • Inflammatory bowel disease 9.82
    • Breast carcinoma 7.85
    • Colonic neoplasm 7.04
    • Ovarian Cysts 5.39
    • Uterine fibroid 5.37
    • Arthritis, Experimental 4.84
    • Amyotrophic lateral sclerosis 1 4.83
    • Diabetes Mellitus, Type 2 4.54
    • Renal cell carcinoma 4.51
    • Glomerulonephritis 4.4
    • Papilloma 4.28
    • Liver Cirrhosis 4.09
    • Status Epilepticus 4.09
    • HIV Infections 4.03
    • Skin Neoplasms 3.94
    • Cocaine dependence 3.83

Genes:

  • ODC1
  • JUND
  • SFRP1
  • SFRP2
  • SFRP4
  • GATA5
  • SFRP5
  • SMS gene-involved in the production of spermine, which is a type of small molecule called a polyamine.
  • SAT1 gene-an enzyme in the catabolic pathway of polyamine metabolism.
  • TGM6 gene-cross-linking of proteins and the conjugation of polyamines to proteins.
  • MTAP gene-This gene encodes an enzyme that plays a major role in polyamine metabolism.